abstract：BACKGROUND AND OBJECTIVE:Children with Crohn disease (CD) often undergo cross-sectional imaging during clinical evaluation. Magnetic resonance enterography (MRE) is becoming the preferred radiologic assessment due to the lack of radiation exposure; however, there are few data in children with CD comparing MRE with obje...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sauer CG,Middleton JP,Alazraki A,Udayasankar UK,Kalb B,Applegate KE,Martin DR,Kugathasan S

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:The geometric mean is the recommended method for calculating gastric emptying in adults to correct for variable attenuation during the study. In children, it has been reported that a single posterior acquisition is sufficient. Our objective was to evaluate the relation between the values of gastric emptying ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Drubach LA,Kourmouzi V,Cao X,Zurakowski D,Fahey FH

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Rotavirus (RV)-induced diarrhea poses a major health problem, particularly to infants. An effective measure to prevent RV infection is to consume breast milk with higher levels of protective IgA. We therefore examined whether Lactobacillus gasseri SBT2055 (LG2055) could augment immunoglobulin (Ig) A levels a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kadooka Y,Tominari K,Sakai F,Yasui H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with cystic fibrosis (CF) have low levels of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) in plasma or red blood cells (RBC), as also seen in other chronic and acute liver diseases. The differences may be more pronounced in CF transmembrane conductance regulator protein (CFTR)-reg...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jørgensen MH,Ott P,Michaelsen KF,Porsgaard T,Jensen F,Lanng S

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Calprotectin is a calcium- and zinc-binding protein and a marker in faeces of gastrointestinal inflammation. Reference values have been established in children older than 4 years. The aim of the present study was to determine the concentration of faecal calprotectin (FC) in human immunodeficiency virus (HIV)...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hestvik E,Olafsdottir E,Tylleskar T,Aksnes L,Kaddu-Mulindwa D,Ndeezi G,Tumwine JK,Grahnquist L

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Esophageal strictures in children are serious and require specialized care. Peptic stricture is most common in our context, whereas caustic and congenital strictures are rare. The present study reports our experience in esophageal endoscopic dilation while specifying the causes of esophageal strictures as wel...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lakhdar-Idrissi M,Khabbache K,Hida M

更新日期：2012-06-01 00:00:00

abstract：:Hepatitis C virus (HCV) is an RNA virus that affects >180 million individuals worldwide with a high propensity for chronic infection. Children with HCV infection differ from adults in several ways including some modes of transmission, rates of clearance, progression of fibrosis, and the duration of potential chronic i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mack CL,Gonzalez-Peralta RP,Gupta N,Leung D,Narkewicz MR,Roberts EA,Rosenthal P,Schwarz KB,North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:We prospectively evaluated incidence of prolonged (>28 days) parenteral nutrition (PN), associated complications, and significance of parenteral plant sterols (PS) in neonatal intestinal failure-associated liver disease (IFALD) compared with children. METHODS:We recruited 28 neonates (mean age 50 days, rang...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kurvinen A,Nissinen MJ,Andersson S,Korhonen P,Ruuska T,Taimisto M,Kalliomäki M,Lehtonen L,Sankilampi U,Arikoski P,Saarela T,Miettinen TA,Gylling H,Pakarinen MP

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Less than one-tenth of the carriers of the risk genes HLA-DQ2 or HLA-DQ8 develop celiac disease, suggesting that other genetic and environmental factors are important in the pathogenesis. The role of gut microbiota has been addressed previously with inconsistent findings. Our aim was to evaluate microbiota, ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kalliomäki M,Satokari R,Lähteenoja H,Vähämiko S,Grönlund J,Routi T,Salminen S

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the incidence of peptic ulcer bleeding (PUB) in pediatric patients. METHODS:A hospital inpatient database, Premier Perspective, and an insurance claims database, MarketScan, were analyzed to estimate upper and lower limits for the annual incidence of PUB in the ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Brown K,Lundborg P,Levinson J,Yang H

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to examine the effects of early and high intravenous (IV) amino acid (AA) supplementation on growth, health, and neurodevelopment of extremely-low-birth-weight (ELBW) infants throughout their first 2 years of life. METHODS:Infants were prospectively randomized in a double-mas...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Blanco CL,Gong AK,Schoolfield J,Green BK,Daniels W,Liechty EA,Ramamurthy R

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:There are limited data on health-related quality of life (HRQOL) in pediatric patients with long-standing pancreatitis (including acute relapsing and chronic pancreatitis) using age-appropriate measurement instruments. METHODS:We evaluated HRQOL in children with long-standing pancreatitis using the PedsQL 4...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pohl JF,Limbers CA,Kay M,Harman A,Rollins M,Varni JW

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Intestinal epithelial restitution is the first part in the process of mucosal repair after injury in the intestine. Integrity of the intestinal mucosal barrier is important as a first line of defense against bacteria and endotoxin. Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Richter JM,Schanbacher BL,Huang H,Xue J,Bauer JA,Giannone PJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND AIM:A select group of children with short bowel syndrome (SBS) and intestinal failure-associated liver disease (IFALD) fulfill the criteria for isolated liver transplantation (iLTx). Long-term results in this group of patients have not been reported. METHODS:A retrospective study of the medical records ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Taha AM,Sharif K,Johnson T,Clarke S,Murphy MS,Gupte GL

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:The diagnosis of celiac disease (CD) is based on the histological identification of gluten-sensitive enteropathy and detection of anti-tissue transglutaminase antibodies (tTGA) and/or endomysial antibodies. Serial measurements of tTGA are now recommended as a follow-up strategy to monitor compliance with a g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Candon S,Mauvais FX,Garnier-Lengliné H,Chatenoud L,Schmitz J

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Polymorphonuclear leukocytes (PMN) feature prominently in the mucosa, including in crypt abscesses, of patients with inflammatory bowel disease, yet the mediators that are responsible for this migration are unknown. We discovered that CXCR2 chemokines (reportedly elevated in the mucosa) have reduced potency ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Stadnyk AW,Carrigan SO,Otley AR

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Dexlansoprazole MR 30  mg once daily (QD) is approved in adults for the treatment of symptomatic nonerosive gastroesophageal reflux disease (GERD) and maintenance of healed erosive esophagitis (EE); 60  mg is approved for healing EE. The present study assesses the pharmacokinetic (PK) profile and safety of d...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kukulka M,Wu J,Perez MC

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:P-glycoprotein (P-gp), the functional product of the multidrug resistance gene (MDR), is a transmembrane protein that extrudes substrates from the intracellular environment. P-gp is expressed on the apical surface of epithelial cells and on cells from the hematopoietic lineage. Human MDR polymorphisms have be...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Staley EM,Dimmitt RA,Schoeb TR,Tanner SM,Lorenz RG

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:The response to hepatitis A vaccine has not been studied in children with celiac disease (CD). The aim of the present study was to evaluate the immunogenicity of an inactivated hepatitis A virus (HAV) vaccine and the effect of the human leukocyte antigen (HLA) type on immunogenicity in children with CD. PAT...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sari S,Dalgic B,Basturk B,Gonen S,Soylemezoglu O

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine whether an oral treatment with a commercial pharmaceutical product containing Saccharomyces boulardii would reduce the duration of diarrhea in infants with acute diarrhea. PATIENTS AND METHODS:In the present double-blind, placebo-controlled study, 186 infants, 6 to 48 mo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Corrêa NB,Penna FJ,Lima FM,Nicoli JR,Filho LA

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to validate a brief Bowel Habit Questionnaire (BHQ) with prospectively obtained data from a 14-day diary and to determine whether the BHQ predicts the development of medically significant constipation (MSC) during the following year. MATERIALS AND METHODS:The BHQ was distributed to ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wald ER,Jagodzinski TD,Moyer SC,Wald A,Eickhoff JC,Edmonson MB

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:There are few data on pediatric celiac disease in the United States. The aim of our study was to describe the presentation of celiac disease among children with a normal and an elevated body mass index (BMI) for age, and to study their BMI changes following a gluten-free diet (GFD). PATIENTS AND METHODS:One...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Reilly NR,Aguilar K,Hassid BG,Cheng J,Defelice AR,Kazlow P,Bhagat G,Green PH

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Assessment of intra- and interobserver agreement in multiple intraluminal impedance (MII) measurement between investigators from different institutions. METHODS:Twenty-four 18- to 24-hour MII tracings were randomly chosen from 4 different institutions (6 per center). Software-aided automatic analysis was pe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pilic D,Höfs C,Weitmann S,Nöh F,Fröhlich T,Skopnik H,Köhler H,Wenzl TG,Schmidt-Choudhury A

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Bone mineral deficiency continues to occur in extremely-low-birth-weight (ELBW) infants despite formulas enriched in calcium (Ca) and phosphorus (P). This study tested whether extra enteral Ca supplementation increases bone mineral content (BMC) and prevents dolichocephalic head flattening and ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Carroll WF,Fabres J,Nagy TR,Frazier M,Roane C,Pohlandt F,Carlo WA,Thome UH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The spectrum and severity of idiosyncratic drug-induced liver injury (DILI) in children are not well established. PATIENTS AND METHODS:The DILIN (Drug-Induced Liver Injury Network) Prospective Study is a longitudinal multicenter study designed to determine the etiologies, risk factors, and outcomes of suspe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Molleston JP,Fontana RJ,Lopez MJ,Kleiner DE,Gu J,Chalasani N,Drug-Induced Liver Injury Network.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The majority of children with Hirschsprung disease (HD) after corrective surgery (CS) develop protracted defecation disorders (DDs) such as constipation, fecal incontinence, and/or enterocolitis. The aim of this investigation was to determine the diagnoses, therapies, and long-term clinical out...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Chumpitazi BP,Nurko S

更新日期：2011-07-01 00:00:00

abstract：:Choline deficiency leads to steatohepatitis, elevated transaminases, susceptibility to septic shock, and an increased risk of central catheter thrombosis. Children with intestinal failure (IF) are at risk for choline deficiency. In an unblinded, open-label study, we studied 7 children with IF on parenteral nutrition, ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Guerrerio AL,Mattis L,Conner KG,Hampsey J,Stasinopoulos DM,DeJong R,Boctor EM,Sheth S,Hamper UM,Scheimann AO

更新日期：2011-07-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are characterized by the invasion of leukocytes into the intestinal mucosa. However, a mixed inflammatory picture is observed that includes neutrophils, lymphocytes, monocytes, and eosinophils. To this day, the role of eosinophils in health and in disease remains unclear. Investigatio...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Woodruff SA,Masterson JC,Fillon S,Robinson ZD,Furuta GT

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Acute pancreatitis (AP) can be a rare extraintestinal manifestation of inflammatory bowel disease (IBD). There are only a few reports of AP presenting before the diagnosis of IBD. We aimed to characterize the demographic, clinical, and laboratory data of patients with IBD in whom AP preceded d...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Broide E,Dotan I,Weiss B,Wilschanski M,Yerushalmi B,Klar A,Levine A

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Button battery ingestions are potentially life threatening for children. Catastrophic and fatal injuries can occur when the battery becomes lodged in the esophagus, where battery-induced injury can extend beyond the esophagus to the trachea or aorta. Increased production of larger, more powerful button batte...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Brumbaugh DE,Colson SB,Sandoval JA,Karrer FM,Bealer JF,Litovitz T,Kramer RE

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:Beginning in March 2002, we initiated steroid-free lymphocyte depleting immunosuppression with rabbit anti-human thymocyte globulin (rATG) for all children who received an intestinal transplant (ITx). The purpose of the present study was to determine whether this treatment regimen supported growth. Because s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Nucci AM,Strohm S,Squires RH,Mazariegos GV,Sun Q,Sindhi R

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Pediatric Rome III criteria of functional dyspepsia (FD) has eliminated the mandatory use of upper endoscopy and recommended a symptom-based approach. In the absence of alarm symptoms, FD can be positively diagnosed in children having normal physical findings without exclusionary investigations. We aimed to i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tam YH,Chan KW,To KF,Cheung ST,Mou JW,Pang KK,Wong YS,Sihoe JD,Lee KH

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of the present study was to evaluate proinflammatory and anti-inflammatory cytokine levels in children with irritable bowel syndrome (IBS). PATIENTS AND METHODS:Thirty-five children with IBS (17 diarrhea-predominant, 7 constipation-predominant, and 11 mixed type) and 25 healthy children as ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hua MC,Lai MW,Kuo ML,Yao TC,Huang JL,Chen SM

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the adequacy of polyunsaturated fatty acid intake by rural Bangladeshi children 24 to 48 months old in relation to their breast-feeding status. MATERIALS AND METHODS:Multistage sampling was used to select a representative sample of children 24 to 48 months of age from 2 rur...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Yakes EA,Arsenault JE,Islam MM,Ahmed T,German JB,Drake C,Hossain MB,Lewis BL,Rahman AS,Jamil KM,Brown KH

更新日期：2011-03-01 00:00:00

abstract：:Most children with chronic hepatitis C are infected vertically, have a low natural seroconversion rate, and carry a lifetime risk of cirrhosis and cancer. Affected children are usually asymptomatic, and histological findings are mild with a low risk of progression, although 5% develop significant liver disease in chil...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wirth S,Kelly D,Sokal E,Socha P,Mieli-Vergani G,Dhawan A,Lacaille F,Saint Raymond A,Olivier S,Taminiau J

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Eosinophilic esophagitis (EE) is characterized by marked esophageal mucosal eosinophilia on histological examination. Although the clinical and histological features of EE are increasingly recognized, the overlap of clinical symptoms and histological findings with gastroesophageal reflux diseas...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Li-Kim-Moy JP,Tobias V,Day AS,Leach S,Lemberg DA

更新日期：2011-02-01 00:00:00

abstract：:Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid reflux events. pH-MII technology is especially useful in the postprandial period or at other times when gastric contents are nonacidic.pH...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mousa HM,Rosen R,Woodley FW,Orsi M,Armas D,Faure C,Fortunato J,O'connor J,Skaggs B,Nurko S

更新日期：2011-02-01 00:00:00

abstract：:Infliximab is frequently used to treat both inflammatory bowel disease (IBD) and psoriasis. We reviewed the medical records of 73 children with IBD receiving infliximab therapy and identified 6 (8%) cases of infliximab-induced psoriasis. Five (83%) had Crohn disease and 4 (67%) were girls. The psoriatic lesions appear...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hiremath G,Duffy L,Leibowitz I

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Functional gastrointestinal disorders (FGIDs) are common in children. Their pathogenesis remains unknown and is most likely multifactorial. We hypothesized that noninfectious causes of inflammation affecting the gastrointestinal (GI) tract early in life, such as cow's-milk allergy (CMA), can predispose to th...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Saps M,Lu P,Bonilla S

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The high prevalence of celiac disease (CD) prompted us to evaluate a new, noninvasive disease screening strategy. The aim was to identify CD in 6- to 8-year-old children for a timely diagnosis, start gluten-free diet (GFD) in compliant subjects, achieve the growth target, and prevent CD complications. METHOD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bonamico M,Nenna R,Montuori M,Luparia RP,Turchetti A,Mennini M,Lucantoni F,Masotti D,Magliocca FM,Culasso F,Tiberti C

更新日期：2011-01-01 00:00:00